ABSTRACT
Objective:To explore risk factors for high risk ventricular arrhythmias (HRVA)after emergency percuta-neous coronary intervention (PCI)in patients with ST elevation acute myocardial infarction (STEMI).Methods:The clinical data of 176 STEMI patients undergoing PCI were retrospectively analyzed.According to presence or not of HRVA after PCI,they were divided into HRVA group (n=34)and no HRVA group (n=142).Single factor and multifactor Logistic regression analysis were used to analyze risk factors for HRVA.Results:Compared with no HRVA group,there were significant rise in levels of serum creatinine [SCr,(86.43±21.26)mmol/L vs.(96.67± 20.85)mmol/L],glycosylated hemoglobin A1 [HbA1c,(6.13 ± 1.53)% vs.(6.75 ±0.74)%],white blood cell count [(10.09±3.34)109/L vs.(11.73±3.42)109/L]and percentage of Killip class VI (2.94% vs.14.7%),and significant reduction in level of low density lipoprotein cholesterol [(3.16±0.92)mmol/L vs.(2.75±0.87)mmol/L]in HRVA group,P <0.05 or <0.01;multifactor Logistic regression analysis indicated that HbA1c,white blood cell count,cardiac function Killip class and SCr were independent risk factors for HRVA after PCI in STEMI pa-tients (OR=4.012~7.145,P <0.05 or <0.01).Conclusion:Glycosylated hemoglobin A1,white blood cell count, cardiac function grading and creatinine are closely correlated with occurrence of HRVA after emergency PCI in STEMI patients.Timely treatment can reduce occurrence of HRVA.
ABSTRACT
Objective:To explore risk factors for high risk ventricular arrhythmias (HRVA)after emergency percuta-neous coronary intervention (PCI)in patients with ST elevation acute myocardial infarction (STEMI).Methods:The clinical data of 176 STEMI patients undergoing PCI were retrospectively analyzed.According to presence or not of HRVA after PCI,they were divided into HRVA group (n=34)and no HRVA group (n=142).Single factor and multifactor Logistic regression analysis were used to analyze risk factors for HRVA.Results:Compared with no HRVA group,there were significant rise in levels of serum creatinine [SCr,(86.43±21.26)mmol/L vs.(96.67± 20.85)mmol/L],glycosylated hemoglobin A1 [HbA1c,(6.13 ± 1.53)% vs.(6.75 ±0.74)%],white blood cell count [(10.09±3.34)109/L vs.(11.73±3.42)109/L]and percentage of Killip class VI (2.94% vs.14.7%),and significant reduction in level of low density lipoprotein cholesterol [(3.16±0.92)mmol/L vs.(2.75±0.87)mmol/L]in HRVA group,P <0.05 or <0.01;multifactor Logistic regression analysis indicated that HbA1c,white blood cell count,cardiac function Killip class and SCr were independent risk factors for HRVA after PCI in STEMI pa-tients (OR=4.012~7.145,P <0.05 or <0.01).Conclusion:Glycosylated hemoglobin A1,white blood cell count, cardiac function grading and creatinine are closely correlated with occurrence of HRVA after emergency PCI in STEMI patients.Timely treatment can reduce occurrence of HRVA.